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【摘要】 目的：觀察澤蛭降壓膠囊治療H型高血壓病痰濕壅盛證的臨床療效。方法：對照組30例西醫(yī)常規(guī)治療，治療組30例在對照組治療的基礎(chǔ)上加服澤蛭降壓膠囊，觀察兩組血壓水平、臨床癥候、Hcy及CRP濃度的癥候變化情況。結(jié)果：治療組在血壓控制、臨床癥候的改善、Hcy及CRP水平的下降等方面均明顯優(yōu)于對照組(P<O．05)。結(jié)論：澤蛭降壓膠囊治療H型高血壓病痰濕壅盛證療效顯著、Hcy及CRP水平的下降顯著。
【關(guān)鍵詞】高血壓??；痰濕壅盛證； Hcy及CRP水平；中醫(yī)藥療法；澤蛭降壓膠囊
Effect of Zezhi Antihypertensive Capsule on 30 Cases of H-type Hypertension of Phlegm and Dampness Accumulation Syndrome
Cao Ying Li Xiaowei,Fu Lichao
Cardiology Department, Hengyang Municipal Hospital of Traditional Chinese Medicine, Hengyang, Hunan, 421001, China
Abstract:
Objective: To observe the clinical effect of Zezhi antihypertensive capsule on H-type hypertension in syndrome of phlegm and dampness accumulation.
Method: The control group with 30 cases are treated by routine treatment of western medicine(WM), whereas the treatment group with 30 cases are added with Zezhi antihypertensive capsule. Indexes of clinical symptoms, blood pressure, homocysteine(Hcy) and c-reactive protein(CRP) are observed.
Results: The indexes in the treatment group is significantly better than those in the control group in symptom improvement, blood pressure control, and decrease of Hcy and CRP levels (P<0.05).
Conclusion: Zezhi antihypertensive capsule has a good effect on H-type hypertension of phlegm and dampness accumulation syndrome and can obviously reduce the Hcy and CRP levels.
Key words: Hypertension; phlegm and dampness accumulation syndrome, homocysteine; c-reactive protein; traditional chinese medicine; Zezhi antihypertensive capsule.
H型高血壓是指伴有血漿同型半胱氨酸升高(Hcy>10umol/L)的原發(fā)性高血壓[ 1 ]，在我國占高血壓人群的75%。同型半胱氨酸是甲硫氨酸的中間代謝產(chǎn)物，它可引起血管內(nèi)皮功能紊亂、脂質(zhì)過氧化、增高血小板的粘附性，導(dǎo)致或加速動脈粥樣斑塊的形成，從而導(dǎo)致心腦血管疾病劇增。筆者總結(jié)了多年的臨床經(jīng)驗，擬定了澤蛭降壓膠囊治療H型高血壓病痰濕壅盛證，旨在化痰活血、平肝補腎，